Vulkan (Preferred for modern GPUs) or Direct3D 11/12.
This comprehensive overview covers everything you need to know about the game, the translation project, and how to set it up. What is Generation of C.E.? Vulkan (Preferred for modern GPUs) or Direct3D 11/12
For physical PS2 consoles, you would also need a way to play backup discs, such as FreeDVDBoot, ESR patching, or a modchip. the translation project